RT - Journal TY - JOUR A1 - Ravikumar, Gopalakrishnan A1 - Naveen Prasad, Gopalakrishnan A1 - Sugapradha, Gopalakrishnan A1 - Sivakami, Thiagarajan T1 - Primary neuroendocrine carcinoma of the breast: A case report and review of literature YR - 2015/10/1 JF - Archives of International Surgery JO - Arch Int Surg SP - 224 OP - 227 VO - 5 IS - 4 UL - https://www.archintsurg.org/article.asp?issn=2278-9596;year=2015;volume=5;issue=4;spage=224;epage=227;aulast=Ravikumar;t=5 DO - 10.4103/2278-9596.174676 N2 - Neuroendocrine tumors of the breast are rare, accounting for less than 0.1% of all breast cancer and less than 1% of all neuroendocrine (NE) tumors. The papillary NE carcinoma of the breast (NECB) with classic morphological and phenotypic features is rare. We describe a case of a 45-year-old woman admitted with a lump in the left breast, initially diagnosed by fine-needle aspiration cytology (FNAC) as intraductal carcinoma. After undergoing modified radical mastectomy, the histopathology showed evidence of alveolar-type primary NECB. A 16-month follow-up of the patient showed no evidence of metastasis. The in situ component of primary NECB may prevail in a core biopsy sample increasing the probability of underdiagnosing this tumor preoperatively. Misdiagnosing primary NECB is detrimental because patients may not receive the optimal adjuvant treatment they need. ER -