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Year : 2019  |  Volume : 9  |  Issue : 1  |  Page : 1-4

Clinical presentation of gallstone disease: Evidence from a case-control study

1 Department of Community Medicine, Dr Baba Saheb Ambedkar Medical College and Hospitals, Rohini, Delhi, India
2 Department of Community Medicine, LHMC and Associated Hospitals, New Delhi, India
3 Department of General Surgery, LHMC and Associated Hospitals, New Delhi, India

Correspondence Address:
Dr. Manish K Goel
Department of Community Medicine, LHMC, New Delhi 110 001
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ais.ais_26_19

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Background: Gallstone disease (GSD) is defined as the presence of one or more stones in the gallbladder. Prevalence of GSD in the adult population ranges from 6% to 9% in India. The present study was aimed to know the association of abdominal symptoms and GSD. Patients and Method: We conducted a case-control study from January 2013 to December 2013 among 120 cases and the same number of controls. Study subjects were selected from outpatient department (OPD) of general surgery. Data was collected by a self-designed pretested interview schedule, to assess sociodemographic profile, personal history, medical history, physical examination including anthropometry. Logistic regression was used for univariate and multivariate analysis to find out different symptoms and analyze the independent association of these symptoms with GSD. Results: We enrolled 120 cases and the same number of age and sex matched controls. 69.2% of the cases were females and 30.8% were males. Univariate as well as multivariate logistic regression analysis of presenting symptoms among study subjects showed only intolerance to fatty food (P = 0.000) and epigastric or hypochondric pain (P = 0.000) were found to be statistically significantly associated with gallstone disease. Conclusion: Biliary colic, consisting of sudden onset of pain in the epigastric or right hypochondric region lasting for more than 30 minutes is a good predictor of gallstone disease along with intolerance to fatty or spicy food.

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