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Year : 2017  |  Volume : 7  |  Issue : 3  |  Page : 111-114

Death resulting from low-grade midgut carcinoid tumor: Autopsy findings and review of the literature

1 Department of Pathology and Forensic Medicine, Lagos State University Teaching Hospital, Lagos, Nigeria
2 Department of Pathology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria

Correspondence Address:
Dr. Soyemi Sunday Sokunle
Department of Pathology and Forensic Medicine, Lagos State University Teaching Hospital, Ikeja-Lagos
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ais.ais_42_17

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Well-differentiated neuroendocrine tumors of the midgut are generally known as midgut carcinoids. These endocrine tumors have characteristic clinicopathological features with majority elaborating serotonin, present at an advanced age, and are frequently associated with carcinoid syndrome. We report an autopsy case of low-grade (G1) midgut carcinoid tumor presenting as carcinoid syndrome in a 64-year-old patient who presented with abdominal distension, diarrhea, body pain, and vomiting. Autopsy findings show a yellow tan tumor in the distal ileum measuring 0.5 × 0.5 × 0.1 cm. Histology shows tumor to be carcinoid and strongly positive for immunohistochemical markers chromogranin and cytokeratin and negative for S-100 protein.

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