CASE REPORT |
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Year : 2017 | Volume
: 7
| Issue : 3 | Page : 111-114 |
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Death resulting from low-grade midgut carcinoid tumor: Autopsy findings and review of the literature
Soyemi Sunday Sokunle1, Saad Aliyu Ahmed2, Adoke Kasimu Umar2
1 Department of Pathology and Forensic Medicine, Lagos State University Teaching Hospital, Lagos, Nigeria 2 Department of Pathology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
Correspondence Address:
Dr. Soyemi Sunday Sokunle Department of Pathology and Forensic Medicine, Lagos State University Teaching Hospital, Ikeja-Lagos Nigeria
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ais.ais_42_17
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Well-differentiated neuroendocrine tumors of the midgut are generally known as midgut carcinoids. These endocrine tumors have characteristic clinicopathological features with majority elaborating serotonin, present at an advanced age, and are frequently associated with carcinoid syndrome. We report an autopsy case of low-grade (G1) midgut carcinoid tumor presenting as carcinoid syndrome in a 64-year-old patient who presented with abdominal distension, diarrhea, body pain, and vomiting. Autopsy findings show a yellow tan tumor in the distal ileum measuring 0.5 × 0.5 × 0.1 cm. Histology shows tumor to be carcinoid and strongly positive for immunohistochemical markers chromogranin and cytokeratin and negative for S-100 protein.
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