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Year : 2015  |  Volume : 5  |  Issue : 4  |  Page : 224-227

Primary neuroendocrine carcinoma of the breast: A case report and review of literature

Department of Plastic and Reconstructive Surgery, Thanjavur Medical College, Thanjavur, Tamil Nadu, India

Correspondence Address:
Dr. Gopalakrishnan Ravikumar
54-Shanthi Nagar, Thanjavur - 613 006, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-9596.174676

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Neuroendocrine tumors of the breast are rare, accounting for less than 0.1% of all breast cancer and less than 1% of all neuroendocrine (NE) tumors. The papillary NE carcinoma of the breast (NECB) with classic morphological and phenotypic features is rare. We describe a case of a 45-year-old woman admitted with a lump in the left breast, initially diagnosed by fine-needle aspiration cytology (FNAC) as intraductal carcinoma. After undergoing modified radical mastectomy, the histopathology showed evidence of alveolar-type primary NECB. A 16-month follow-up of the patient showed no evidence of metastasis. The in situ component of primary NECB may prevail in a core biopsy sample increasing the probability of underdiagnosing this tumor preoperatively. Misdiagnosing primary NECB is detrimental because patients may not receive the optimal adjuvant treatment they need.

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