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Year : 2012  |  Volume : 2  |  Issue : 2  |  Page : 79-82

Bacteriological profile of cholectystitis and their implication in causing post-operative wound infections

1 Department of Microbiology, Vijayanagar Institute of Medical Sciences, Cantonment, Bellary, Karnataka, India
2 Bidar Institute of Medical Sciences, Bidar, Karnataka, India

Correspondence Address:
Rudresh M Shoorashetty
Department of Microbiology, Bidar Institute of Medical Sciences, Bidar - 585 401, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-9596.110028

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Background: Cholecystitis is a common indication for major abdominal surgeries. It may occur with or without obstruction of common bile duct. Obstruction leads to secondary bacterial infection of bile. Bactibilia is an important predisposing factor for post-operative complications. Hence, this study was designed to determine the prevalence of bacteria in bile samples of cholecystitis patients and to correlate bactibilia and post-operative wound infection. Materials and Methods: Bile samples collected intra-operatively were subjected to gram stain, culture, and antibiotic sensitivity testing. The patients were followed-up for post-operative complications. If post-operative wound infection was found, cultures were done and correlated with bacteria isolated from bile samples. Results: Bactibilia was found in 27/50 (52%) of patients. Polymicrobial flora was found in 10% of bile samples. Escherichia coli, Klebsiella pneumoniae and Enterococcus faecalis were the predominant organisms isolated. None of the anaerobes were isolated. Extended spectrum β-lactamase and AmpC β-lactamase (AmpC) production was seen in 47% and 31.5% of Enterobacteriaceae isolates respectively. Post-operative wound infection was found in six (12%) patients who had bactibilia. Combination of piperacillin-tazobactam and amikacin was most effective in prophylactic regimen. Conclusion: The organisms responsible for bactibilia were found to cause post-operative infections in the same patient warranting the use of prophylactic antibiotics in every patient undergoing cholecystectomy. All patients undergoing open cholecystectomy should receive prophylactic antibiotics to prevent post-operative wound infections.

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